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BioNTech Company Profile | Drug Discovery & DDS

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Company Profile

BioNTech
— The first company to win an mRNA approval is shifting toward cancer treatments combining antibodies and ADCs

BioNTech is a COVID vac、 "Comirnaty" jointly developed with Pfizer.First approval as a medicine using mRNA. However, the subsequent sales will be reduced.Net loss of 113,610 millionComment In the end of June 2026€16 billionIn this fund Double specific antibody (co-developed with Bristol Myers Squibb), antibody drug complex (ADC), personalized mRNA cancer immunotherapy, etc. 2025 acquired CureVac of the same mRNA company. In this article, this company isWhat to do with mRNA and its carrier (LNP · lipoplex), and what to doHome We will organize the annual report (Form 20-F), quarter report (Form 6-K) submitted to the US SEC and the official announcement of the company.

Composition: Form 20-F (submitted on March 10, 2026), Form 6-K (submitted on August 4, 2026), Form 6-K (submitted on August 3, 27 and September 14, 2026) as primary information

In this article
  1. Viontech in 30 seconds and standing position in drug discovery and DDS
  2. About logo and company name
  3. Where is this company in the world of drug discovery and DDS?
  4. Size of the company (supporting reduction of COVID vac s with financial strength)
  5. Drug discovery and DDS resources
  6. Past Initiatives
  7. Future plans
  8. What is DDS?
  9. Collaboration mapping of drug discovery and DDS
  10. Technologies, Products and Services
  11. The risk of this company
  12. Glossary/Source/Ins ment and Source Response Table

1. Viontech in 30 seconds and standing position in drug discovery and DDS

NameBioNTech SEEuropean company based on German law (SE)
HeadquartersGermany MainzAn der Goldgrube 12
ListingNasdaq: BNTXADS. Founded in 2008
Categories in this fieldDrug discovery biotech
(Multiple modalities)
mRNA, antibody, ADC, cell therapy
Approved ProductsComirnaty(COVID-19)Joint development with Pfizer. Approval of more than 180 countries and regions
Sales for FY202586 million 28COVID vac s of €195.3 million
FundsEUR 166.4 billionCash equivalents + securities investment (as of June 2026)
Largest Partnership in the Cancer AreaBristol Myers SquibbJoint development of double-specific antibody pumitamig
1 point to press

Businesses related to drug discovery and DDS are largePharmaceutical Company / Biotech / Contract Development Manufacturing (CDMO・CRO)3 types. BioNTechDrug discovery biotechModerna of the same mRNA companyNot bet only mRNA FactsHome 20-F explains its technology as a platform for mRNA immunotherapy and protein medicine (monocrone antibody, double-specific antibody, and ADC). Main axisCancerIt is stated that it is written in. Most of the late items in the cancer areaAntibody and ADCAnd most of them were introduced and acquired from other companies. In other words, BioNTech is known as a company of mRNA, but as of 2026, it is Using COVID vaccine funds, we are trying to change to a cancer treatment company that combines antibody, ADC and mRNA.Comment

2. Logo and company name

BioNTech trademark In this article, we do not reproduce the generated image. Images posted on the header of the official websiteHome img/biontech_logo.svg Contact Us

Note: Company name BioNTech SE "N" and "T" are upper case. Founded in 2008 as Petersberg 91 V AG, renamed BioNTech AG in the same year. In Japanese, it is often referred to as "Biontec". Joint product name with Pfizer ComirnatyComment

Official Site:https://www.biontech.com/int/en/home.html

3. Where is this company in the world of drug discovery and DDS?

3 types of companies involved in drug discovery and DDS In the same "pharmacy company", it is completely different where the drug is made Pharmaceutical Company Drug discovery biotech Research and development From search to approval and sales Create candidates with new modalities and methods Contract development and manufacturing of other drugs Eli Lilly/Novo Nordisk Pfizer Alnylam/Arvinas Moderna/Insilico Lonza/Samsung Biologics AppTec Secondary clinical and sales network funding Specific technical base depth Mass production capability for equipment and regulation Sales can be reduced rapidly due to the lack of patents Rely on partnering with funds for late development Disco・ation of customer development and impact of policy BioNTech is a central drug discovery biotech that expands its axis to antibody and ADC in addition to mRNA. COVID vaccines are sold in conjunction with Pfizer, and in the cancer area, they have acquired a tie-up and acquired a second item.
Figure 1 Position BioNTech with three types of companies involved in drug discovery and DDS. The classification is based on this article, and the company name is an example from the company handled by this series. The calculation of this paperHome BioNTech has a multi-platform of mRNA and protein medicine (antibody and ADC), and the main axis of cancer is based on the form 20-F for the、20 year ending December 2025.

TypeDrug discovery biotechand handle modalitiesmRNA (LNP and lipoplex), double-specific antibody, ADC, cell therapyContact Us FactsHome The 20-F patent chapter contains two types of mRNA carriers. Used for in ious diseases vac sLipid nanoparticles (LNP)Used for cancer immunotherapy (iNeST of individualization, FixVac of ready-made products)RepoplexComment For the same mRNADDSThe technical characteristics of this company. The related basics are handled by the technical commentary "mRNA", "lipid nanoparticles", "antibody medicine and ADC".

4. Scope of the company (supporting the reduction of COVID vac s with financial strength)

The number is the disclosure of the company by international accounting standards (IFRS), and the unit is € million Facts。

Indicator (Million Euro)FY2023FY2024FY2025January to June 2026
Sales3,819.02,751.12,869.9223.7
COVID Vac s―(No translation to the source of this article)2,432.11,995.3118.8
BMS――613.0―
R&D expenses1,783.12,254.22,104.91,108.0
Net income (loss)930.3▲665.3▲1,136.1▲1,352.7
December 31, 2025June 30, 2026
Cash equivalents + securities investmentApprox. 1.7 billion euroEUR 166.4 billion
(full-time conversion)7,807 (including 1,310 doctorate) CureVac (including 664 people)Not specified in quarterly reports
Clinical Programs for Cancer Areas16 programs, 2nd and 3rd phase test 2514 Pivotal Tests
Contact Us

Comirnaty's sales are on BioNTech's profit and loss statementsNot in fullHome Pfizer sells the region as described in 20-FBioNTech's share of the total revenue of partnerscalculated as " FactsHome Therefore, the number of "COVID vac " above is not the market size of the vac or the sales amount. The sales of 2025 exceeded the previous year.T lead income €613 millionCOVID vac。 itself is reduced by 18%. 2026 sales forecast€16 Billion to €19 Billionlowered to As of March, EUR 20 billion to € 23 billion Undetermined / Future。

5. Drug discovery and DDS resources

Resource Types
PersonFull-time conversion7,807 people(December 31, 2025). 2,634 business operations including 1,050 clinical development, 1,497 research and pre ical, and manufacturing. 6,317 European, 688 North America, 622 Asian and Australian, 180 AfricanFacts
People (Research and manufacturing base)Head Office Mainz (East Wing, over 300 mRNAs), Marburg (about 450 people), Ider-Overstein BioNTech IMFS (about 500 people), Berlin (peptides), China's Zhuhai/Nantong, Rwanda Kigali (under construction), Melbourne, Australia (under construction)Facts
Gold (R&D expenses)FY2025 €24.9 millionHome 2026 is expected to pay €20 billion to €23 billion after adjustmentFacts
Gold (Manufacturing Equipment)In 2025, we started to integrate and adjust our bases. Year 2026With al from multiple manufacturing sitesDecided the total cost of €6,890 million, including facilities at Marburg and Ida-Overstein.Facts
Biotheus(completed in February 2025, €77.8 million in advance)CureVac(December 2025, stock exchange) complements the ability to design, deliver and manufacture mRNA. InstaFacts
License3 ADCs from DualityBio (HER2, B7H3, TROP2, 2023), Anti-CTLA-4 antibody from OncoC4 ($2 billion prepaid). For LNP, Ac)as is licensed under the patent of University of Pennsylvania (via MRT/CellScript)Facts
Contact UsBMS(pumitamig),mitntech(mRNA iNeST), Pfizer(COVID vac)), RNAnmab(antibody), Regeneron(BNT111 clinical trial)Facts
University and Public FundsTRON, University of Pennsylvania, Gates Foundation, CEPI, La Trobe UniversityFacts
"No description" also results

BioNTech’s research and development costsHow much is used for mRNA, antibody, and ADC?not disclosed Undetermined / FutureHome Financial results for the first half of the year of 2026 are the factors to push the R&D expensespumitamig andgotistobartIn of intangible assets and CureVac. There is no breakdown of the amount,Antibody effects are transferred to the antibody sidecan be read from this explanation.

6. Past Initiatives

TimeHome
Year 2008Established in June and renamed to BioNTech AG in DecemberA company launched by researchers in immunotherapy
Year 2009BioNTech IMFS became a wholly owned subsidiary. GMP manufacturing license for mRNA in 2011Production from early stages
September 2016Partnership between Genentech and iNeSTHome Prepaid and Short-Term Milestones: US$3 billionJoint vac for individualized cancer
Year 2018Acquisition of iNeST manufacturing license at East Wing in Mainz (June)Started manufacturing mRNA per patient. Over 1,700 b
Year 2020Partnership between Pfizer and COVID vaccineHome $72.5 million in prepaid, $113 million in Pfizer shares, half of development costs and total revenueThe world's first mRNA drug approval
March 2021Marburg Plant acquired COVID vaccine solution manufacturing approval from vaccineA factory that can make up a maximum of 30 billion times a year
2023 yearDualityBio and ADC 3 itemsFull-scale entry into ADC in the cancer area
February 2025Completed Biotheus acquisitionPD-L1×VEGF-A double-specific antibody pumitamigSecuring late candidates
June 2025BMS and pumitamig co-development agreementHome $15 billion in advance, $20 billion in fixed payouts by 2028, $76 billion in milestones,Separate costs and risks with majors
August 2025COVID vac for LP.8.1 approved by FDA and EUThe composition has been updated once a year
December 2025Acquisition of CureVac in Stock Exchange(completed 15 December, acquired the remaining shares in January 2026)Compensating for the design, delivery and manufacturing capability of mRNA
March 2026Co-founder Mr. Sha and Mr. TuereyIndependent new companyAnnouncement of the establishment plan. Consultation in the direction of the next generation mRNA rights and technologyCutting the next generation mRNA from the body
Year 20266 pivotal tests (pumitamig 5 or ADC 1) Determines withdrawal from multiple manufacturing sitesResources for the late development of cancer
July to August 2026XFG-compliant COVID vac。 approved by the European Commission (July) and FDA (August 27). Nominated Guido Oelkers (appointed by February 1, 2027) as the next CEO on August 3Enter the mating phase of management

Major clinical trials (the subject matter of this article)

TestPhaseMain evaluation itemsPublished situations (at the point of comparison and evaluation)
BNT122-01(autogene cevumeran、NCT04486378)Phase 2 ctDNA-positive colorectal cancer (stage II high risk/III) after surgery, about 327 peopleDFSControlElapse observationHome The first intermediate analysis (approximately 9 months) exceeds the boundary of unevenness, but continues to test as data unmature. Final analysis postponed in 2027
IMCODE001(autogene cevumeran、NCT03815058)Phase 2 Un ed progressive malignant melanomaUnexpected survival (PFS)ControlPembrolizmab aloneHome Statis significant improvement of key evaluation itemsNot achieved(March 2025)
PRESERVE-003(gotistobart、NCT05671510)Phase 3 Non-Pivotal Phase 1 87 non-small cell lung cancer with pre-treated treatmentTotal survival (OS)ControlDocetaxelHome In 25.4 months, OS median 18.5 months to 10.0 months (HR 0.56, no p=0.0295). The second stage of the Pibutar continues

The results above are written about the company's announcement.This article does not recommend the choice of treatmentHome As of September 2026Unapproved Development ItemsHome Undetermined / Future。

7. Future plans

2026 sales forecast€16 Billion to €19 BillionAugust 2026 BMS’ tie-up revenue of €613 million will be recorded in the third quarter
2026 Research and development costs20 billion to 23 billion euroAfter adjustment. Reduce costs by prioritizing
2030 goalswith multiple approved products
Pharmaceutical Company
Expression of company and CEO no release
Management TeamNew CEO was appointed to February 2027Two co-founders will move to a new company
ProductsHomeStage (as of September 2026)The following sections of the company
pumitamig(BNT327)Double specific antibody (PD-L1×VEGF-A)3rd phase 7 Pivotal8 Global Registration Tests by BMS and the end of 2026 Undetermined / Future
trastuzumab pamirtecan(BNT323)ADC(HER2)2 Phase 3DualityBio and 2026 3rd phase analysis of milk cancer is Q4 2026 Undetermined / Future
elfetabart drozuntecan(BNT324)ADC(B7-H3)Developed (3rd phase, starting May 2026)Docetaxel with castent-resistant prostate Undetermined / Future
gotistobart(BNT316)Anti-CTLA-4 AntibodyDeveloped (3rd phase)The first intermediate analysis of the second stage will be scheduled in 2026 Undetermined / Future
autogene cevumeran(BNT122)Individualized mRNA (repoplex)2nd phase Colon cancer and pancreatic cancerFinal analysis of colorectal cancer test 2027 Undetermined / Future
XFG ComirnatymRNA+LNPU.S.-EU approval2026-2027 Season
Not confirmed

20-F・6-K Undetermined / Future。

Co-founderWhat mRNA technology and rights do you have?and its terms and conditions/with al manufacturing sitesList and Time/ CureVacHow to useProductsApproval timing and sales forecastResearch and development costs by modalities. "BioNTech's cancer treatment drug is EUR 250 million per year"

8. What is this company aiming for drug discovery and DDS?

This includes parts that the company does not directly state.Calculation in the range that can be read from primary informationand write with the basis.

ReadPrimary Information
By 2030Pharmaceutical company with multiple approved productsAnnouncement of Financial Results and CEO Nominated Release “To the Company of Multiple Products by 2030”Facts
Candidates for approvalAntibody and ADC instead of mRNAHomeThe third phase is pumitamig・trastuzumab pamirtecan・elfetabart drozuntecan・gotistobart, and mRNA cancer immunotherapy stays in phase 2
mRNAAntibody effects are transferred to the antibody siderepositioned as20-F is a combination of “combination of heavy-duty compounds of mechanisms of action” as a pillar of the strategy, and the combination of pumitamig and mRNA cancer immunotherapy is described.
Part of next-generation mRNA technologyGrow outside the bodyPlan to contribute to next generation mRNA rights and technology to a new company led by the co-founder
CureVacpatent and formulation technology of mRNAThe face is largeIn the calculation of the acquisition price, EUR 630 million is deducted as the liquidation of existing relationships (contracts and non-contracts). Intangible assets acquired are mainly intellectual property rights and licenses
Production NetworkReduce and repositionat the stageSince 2025, we have decided to withdraw from multiple locations in the first half of 2026.Facts
Only one basis for guessing: accounting for CureVac acquisition

According to 20-F note, BioNTech to CureVac shareholdersADS value of 10.11 million euroContact Us However, it was calculated as "acquisition consideration"€90 millionthe difference€30 millionHome It is separated from corporate bonds as "cleaning existing relationships" FactsHome The breakdown is €418,890 million in unpaid balances based on contractual relationships and €1,140 million in unpaid relationships. 20-F refers to Note 18 for non-contract relationships, and Note 18 describes the history of CureVac Proceedings, which was prosecuting BioNTech in Comirnaty’s patent infringement in July 2022. This paper is for this acquisition.Complementation of mRNA technology and consolidate patent relationships within one companyRead the meaning Undetermined / FutureHome However, the company itself explains the purpose of acquisition as "completion of the ability and technology of design, delivery and manufacturing of mRNA" and does not write patent arrangement.

9. Collaboration mapping of drug discovery and DDS

Partnership with DDS, a drug discovery centered on BioNTech Only relationships with 20-F・6-K and official announcements. No media-based relationships Co-development / Introduction (real line / dark blue) Sales and Supply (Orange) Acquisition BioNTech mRNA・antibody・ADC Pfizer COVID Vac Bristol Myers Squibb pumitamig Genentech(Roche) iNeST DualityBio (China) ADC 3 items OncoC4 anti-CTLA-4 antibody Acuitas・TRON LNP CureVac・Biotheus Acquisition of mRNA antibody in 2025 Fosun Pharma Sales of vac s in China
Figure 2 Collaboration between drug discovery and DDS centered on BioNTech. Source: Form 20-F, December 2025, quarterly report (Form 6-K).Dark blue of the real line jointly developed, introduced, introduced, sold by orange and acquired by dotted wirePfizer is sold in the world other than China, Germany, and Turkey. From Ac is asFat nanoparticles and preparations for ComirnatyTRON is a non-exclusive license and jointly holds patents for mRNA preparations (Repoplex LNP). The relationship between Genmab, Regeneron, Pennsylvania University, Gates Foundation, and CEPI was described in the table of the body.

10. Technologies, Products and Services

Approved products

ProductsMain approval (country, type, time)
Comirnaty(BNT162b2)COVID-19 vac enclosed by modifier nucleotide mRNA in LNP. Joint development with PfizerApproval and emergency use permission in more than 180 countries and regions as of March 2026. Over 50 billion times LP.8.1 version approved by the FDA in August 2025. The European Commission, in July 2026FDA on August 27, 2026approval (high-risk persons over 65 years old, 5 to 64 years old)

Technical base: 4 types of "carryers" and multiple modalities

Technology20-F DescriptionUsed Items
Structure of mRNAPatent applications such as 5' cap, 3' non-translation area, poly A chain, mRNA with reduced uracil content, modifier nucleotideAll mRNA items
Lipid nanoparticles (LNP)Used for COVID vacs, RiboMab which makes antibody in the body with mRNA, and RiboCytokine which makes cytokines. Comirnaty's lipids and preparations are licensed from Ac asComirnaty
RepoplexPreparation for cancer immunotherapy (iNeST, FixVac). Patents jointly held with BioNTech alone or TRONautogene cevumeran、BNT111、BNT113
Manufacture of individualized mRNAMINEZ's East Wing is made by automated paperless mRNA for each patient. Over 1,700 bautogene cevumeran
ADC AntibodyADC is introduced fromalityalityBio. Manufacture of clinical antibody (original medicine and preparation) at Nandori factory in Chinatrastuzumab pamirtecan, pumitamig etc.
Cell Therapy and PeptidesManufactured CAR-T cells in IMFS in less than 35 days. Syn) of peptides in Berlin (approximately twice the capacity of the new plant in September 2025)BNT211
Perspective of material ians: LNP and lipoprex are different

20-F Vac、LNPCancer immunotherapyRepoplexThe patent chapter clearly indicates that mRNA preparation is used. FactsHome In general, LNP is made by rapid mixing ionized fat, lipid, cholesterol, and PEG lipids from ethanol to water phase.Fine particles with mRNA insideComment Repoprex made in advanceA complex that combines positive liposom and mRNA electrolyHome The ratio of fat and mRNA (balance of charge) changes the particle surface charge and destination in the body. When viewed from the material side, the formerdesign and mixing process of lipidsThe latterManagement of liposome quality and mixing ratioIt is a game.

20-F, IMFS in addition to initial clinical preparationsReposom as a precursorIt is written that it is made. Making liposomes in-house reads the premise for managing lipoplex formulations on their own. BioNTechWe do not disclose the lipid composition of our lipoplex or LNPHome The general theory above is a general explanation of this article. It does not indicate the combination of BioNTech-specific. Undetermined / Future。

11. Risks that this company has

Risks
reduced demand for COVID vacsCOVID vac) sales for the first half of 2026 is €1,880 million (euro 2,66 million). The company reduced sales forecast for 2026 due to the weakness of demandFacts
Only one approved productOnly Comirnaty approved products as of September 2026. All cancer items are under developmentFacts
Patent LitigationModerna’s European and English litigation continues. In July 2026, Arbutus/Genevant newly prosecuts Comirnaty patent infringement in Canada and European Unified Patent CourtFacts
Managing DirectorCEO and Chief Medical Officer will move to a new company. After-sales CEO was appointed until February 2027.Facts
Uncertainty of mRNA cancer immunotherapyIMCODE001 has not received major evaluation items, and the colorectal cancer test has exceeded the boundary of unevenness in intermediate analysis (test continues)Facts
Dependency on the productMany of the late items are introduced and acquired from other companies, and the conditions of royalty and joint sales influence the profit
Re ation of manufacturing networkdecide the withdrawal from multiple locations and reduce equipment. Possibility of supplying or sending personnel during retraining

12. Glossary

mRNA
design drawing to make protein into cells. In the vac , the antigen of the pathogen is created in cancer immunotherapy.
LNP
It contains mRNA internally, and it delivers it to cells from decomposition.
Repoplex
A complex that combines positive liposome and nucleic acid electroly. Nature changes with mixing ratio.
iNeST
BioNTech's personalized neo-antigen mRNA immunotherapy. Make each patient according to the mutations of the tumor.
FixVac
BioNTech's ready-made mRNA cancer immunotherapy. Aim for cancer antigens common to many patients.
ADC
A drug that connects antibodies with a linker and selectively delivers it to cancer cells.
Double specific antibodies
Antibodies that combine two different targets simultaneously. pumitamig joins PD-L1 and VEGF-A.
Form 20-F/6-K
Annual reports and extraordinary quarterly reports submitted by foreign companies listed in the US SEC.
Conceptual diagram: Delivering mRNA with two types of lipid carriers (d  particles and compounds combined with membranes), and connecting with antibodies to cancerConcept diagram of AI generation
Figure 3 Concept diagram of multiple modalities strategy of BioNTech (AI generation). We do not copy actual equipment or products.

13. Source

  1. BioNTech SE Form 20-F for the) year ended December 31, 2025 Acquisition, sales, R&D, and net income of BMS, Pfizer,alityntech, DualityBio, OncoC4, sun, patent and license (Ac as, TRON, MRT/CellScript), Biotheus and CureVac. https://www.sec.gov/Archives/edgar/data/1776985/000177698526000017/bntx-20251231.htm
  2. BioNTech SE Quarterly Report for the three and six months ended June 30, 2026 (Form 6-K Attachment Exhibit 99.1, submitted August 4, 2026). Patent litigation, European approval of XFG-compliant vac。s, breakdown of sales, decision of withdrawal from manufacturing base, consultation status of new company, patent litigation. https://www.sec.gov/Archives/edgar/data/1776985/000177698526000055/bntxq22026ex991quarterlyre.htm
  3. BioNTech SE Financial Results for the Second Quarter of FY2026 (Form 6-K Attachment Exhibit 99.1, August 4, 2026). Earnings, R&D, Net Loss, Funds, Revised Outlook for 2026, Status of Pivotal Testing, Update of Pipeline, Targets for 2030 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000054/a991bntx_q22026pressreleas.htm
  4. BioNTech SE Press Release “BioNTech Announces Appointment of Odo Oelkers to Management Board as Chief Executive Officer” (Form 6-K, August 3, 2026). The transition to a new company of co-founder at the time of appointment and appointment of the next CEO. https://www.sec.gov/Archives/edgar/data/1776985/000177698526000051/a991biontechannouncesappoi.htm
  5. Pfizer Inc./BioNTech SE Press Release “Pfizer and BioNTech Receive U.S. FDA Approval for XFG-adapted COVID-19 Vac ” (Form 6-K, August 27, 2026). FDA approved and targeted for XFG-compliant vac。s. https://www.sec.gov/Archives/edgar/data/1776985/000177698526000059/a991bntx_covid-19xfgvarian.htm
  6. BioNTech SE/OncoC4, Inc. Press Release (Form 6-K), September 14, 2026. P。ERVE-003 1st stage of survival data (contrast docetaxel, 25.4 months). https://www.sec.gov/Archives/edgar/data/1776985/000177698526000063/a991260911_bntxwclcxgotist.htm
  7. ClinicalTrials.gov NCT04486378 (2nd phase of autogene cevumeran colon cancer). https://clinicaltrials.gov/study/NCT04486378
  8. BioNTech SE Official website (name and logo) https://www.biontech.com/int/en/home.html

14. Response table of claims and sources

Content
Official name, head office location, listed market, established and renamed in 2008, and changed to SE in 2019FactsSource 1 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000017/bntx-20251231.htm
Policy that focuses on cancer with multiple technology platforms, 16 cancer domains, 2/3 phase 25 superFactsSource 1 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000017/bntx-20251231.htm
Sales of 2023-2025, COVID vacs sales, investment income, R&D expenses, net income, net income, net income, and hand fund of the end of 2025 EUR 172 billionFactsSource 1 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000017/bntx-20251231.htm
COVID vacs sales are calculated as the total profit of the partnerFactsSource 1・2 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000055/bntxq22026ex991quarterlyre.htm
Sales, COVID vaccine sales, R&D expenses, net loss, retained funds at the end of June, pivotal test 14, 2026 target revision, target of 2030FactsSource 3 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000054/a991bntx_q22026pressreleas.htm
7,807 employees (full-time equivalent) and job titles and regional breakdownsFactsSource 1 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000017/bntx-20251231.htm
Production base (Marburg IMFS, East Wing, Berlin, Zhuhai, Nanjing, Kigali, Melbourne) and personnel and capacityFactsSource 1 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000017/bntx-20251231.htm
Decision on withdrawal from multiple manufacturing sites and losses in Marburg Ider-OversteinFactsSource 2 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000055/bntxq22026ex991quarterlyre.htm
Agreement with BMS (prepaid $15 billion, fixed pay $20 billion, milestone up to $76 billion, profit and loss halves)FactsSource 1 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000017/bntx-20251231.htm
Pfizer・Genentech・DualityBio・OncoC4・GenesunFactsSource 1 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000017/bntx-20251231.htm
Acquisition of Biotheus (prepaid €77.8 million) and acquisition of CureVac (equivalent to €10 million in stock, €4 trillion in acquisition, €6 trillion in existing relationships), and €6 trillion in July 2022 by CureVacFactsSource 1 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000017/bntx-20251231.htm
LNP and lipoplex are used in conjunction with Ac, TRON, MRT, and CellScript licenses.FactsSource 1 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000017/bntx-20251231.htm
Approval of Comirnaty approved countries, regions and shipments, and LP.8.1 supported versionsFactsSource 1 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000017/bntx-20251231.htm
XFG-compatible version of FDA approved (August 27, 2026)FactsSource 5 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000059/a991bntx_covid-19xfgvarian.htm
Interim analysis of autogene cevumeran colonic cancer test and postponement of final analysis, result of IMCODE001FactsSource 1・7 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000017/bntx-20251231.htm
Pervive-003 1st stage OS (18.5 months to 10.0 months, HR 0.56, 25.4 months, 87 people)FactsSource 6 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000063/a991260911_bntxwclcxgotist.htm
Nominating the next CEO and moving to a new companyFactsSource 4 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000051/a991biontechannouncesappoi.htm
Patent Litigation with Moderna Arbutus/GenevantFactsSource 2 https://www.sec.gov/Archives/edgar/data/1776985/000177698526000055/bntxq22026ex991quarterlyre.htm
Drug discovery and DDS classification (pharmaceu company / drug discovery biotech / contract development manufacturing and research)The calculation of this paperThis article. Company name is an example of a company handled by this series.
Difference between LNP and lipoplexThe calculation of this paperGeneral explanation by this article. BioNTech-specific formula not included
Under the technology and rights of the new company, the list and time of withdrawal bases, the expected approval period, the R&D expenses for modalities, the lipid composition of LNP and lipoprexUndetermined / FutureNot specified in the source 1-6. No number of media and survey companies https://www.sec.gov/Archives/edgar/data/1776985/000177698526000055/bntxq22026ex991quarterlyre.htm
This approval candidate is based on antibody and ADC.Interpre of this paper from the stage of each item of source 3
Read that mRNA is repositioned to the combination partner of antibodyInterpre of this paper from the description of the combination strategy of Source 1
Read to grow next generation mRNA outside the bodyInterpre of this paper from the description of the new company of Source 1 and 4
Read that CureVac acquires a patent relationshipInterpre of this paper from accounting for acquisition of source 1
Risks related to dependency on the product and return of the production networkInterpre of this document from the affiliation structure of the source 1 and 2 and the description of the withdrawal of the base

Last Updated:September 26, 2026/Troy Technical
All figures in this article are based on the legal disclosure document submitted by BioNTech SE to the US Securities and Exchange Commission (SEC) and the official announcement of the company, ClinicalTrials.gov. We do not use estimates and media-based numbers of survey companies. The "、ulation" section is an interpretation that the article reads from the primary information and is not an announcement of the company. This article is not medical advice.

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