New Technology– category –
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meCAR T cells: City of Hope’s reconfigurable CAR T platform
BIOENGINEER.ORG USA Overview Researchers at City of Hope have developed a preclinical "plug-and-play" CAR T cell platform that can be reconfigured with engineered molecules after administration. Using a molecular docking system, the meCA... -
MEW PCL Scaffolds: High-Density cRBC Biomanufacturing Specs
bioRxiv (preprint) Overview Researchers developed marrow-mimetic melt electrowritten (MEW) polycaprolactone (PCL) scaffolds that recapitulate erythroblastic islands to increase cultured red blood cell (cRBC) production. The platform achi... -
Morphi: AI-driven phenotypic profiling for organoid screening
bioRxiv (preprint) Overview Morphi is an AI-driven framework that infers organoid viability and phenotypic states directly from label-free bright-field microscopy. By combining viability scores with unsupervised morphology and texture fe... -
CHO Cell Bioreactor Model: Fed-batch to Continuous Transfer
bioRxiv (preprint) Overview Researchers have developed a metabolism-informed model for monoclonal antibody (mAb) production that enables the transfer of knowledge from fed-batch to continuous biomanufacturing. By embedding mass balances ... -
DS-CAT Framework: Raman and NIR Fusion for Glucose Sensing
Genetic Engineering & Biotechnology News USA Overview A new multimodal soft-sensing framework using a dual-stream, cross-attention transformer (DS-CAT) architecture has achieved 99% variance explanation in glucose concentration. By fusin... -
ReHeart iPS-derived cardiac sheets: First clinical surgery and timeline
MBS News Japan Overview The first surgical procedure using ReHeart, an iPS cell-derived cardiac sheet, has been performed on a female patient in her 50s. Developed by Curopis, the technology received conditional and time-limited approval... -
3D Cell Painting: Uppsala University’s method for drug screening
Drug Target Review Sweden Overview Researchers at Uppsala University have developed a 3D Cell Painting method that distinguishes drug effects missed by conventional 2D cultures. By analyzing single cells within 3D spheroids, the team ide... -
CAR-T Cell Therapy: Solid Tumour Progress and 2026 Milestones
BIOENGINEER.ORG USA Overview CAR-T cell therapy has achieved its first regulatory approval for a solid tumour with Satri-cel for gastric cancer in June 2026. While blood cancer treatments are established, the field now focuses on overcom... -
Celleo Larkem V40: Automated Vial Filling for Cell Therapy
Lab+Life Scientist Australia Overview Celleo's Larkem V40 has won a 2026 Australian Good Design Award for automating the vial filling process in cell therapy manufacturing. The system reduces filling time for 40 vials from half a day to ... -
Trispecific CAR-T Cells: CD19/CD20/CD22 Trial Results from OSUCCC
RegMedNet USA Overview A first-in-human Phase I trial has demonstrated that trispecific CAR-T cells targeting CD19, CD20, and CD22 induce durable responses in patients with relapsed B-cell lymphoma. The construct incorporates OX40 co-sti...
