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OECD (Organisation for Economic Co-operation and Development) | Institution Profile

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INSTITUTION PROFILE / NANOTECHNOLOGY

OECD (Organisation for Economic Co-operation and Development)
The intergovernmental body that aligns nanomaterial test methods and the mutual acceptance of test data among its members

The OECD is an intergovernmental organisation with its Secretariat in Paris and 38 member countries. It does not approve or ban nanomaterials. Through its Working Party on Manufactured Nanomaterials (WPMN), it develops test guidelines, assessment guidance and a framework for international co-operation on nanomaterial safety. Its strongest mechanism is the Mutual Acceptance of Data (MAD) system, under which a test done once is accepted by other participating countries. But OECD documents differ in force: a Decision can bind, a Recommendation does not. The 2013 Council act on safety testing and assessment of manufactured nanomaterials is a Recommendation and is not legally binding. This profile looks at one question only: how far the OECD's influence over nanotechnology actually reaches, in terms of the kind of power it holds and where that power applies.

Sources: the OECD's website (organisation pages, the nanomaterials topic page, the pages on test guidelines, mutual acceptance of data and NANOMET), the OECD Legal Instruments compendium (Council Decision OECD/LEGAL/0194 and Council Recommendation OECD/LEGAL/0400) and OECD reports. Last updated October 2026.

Educational illustration: OECD (Organisation for Economic Co-operation and Development)
Conceptual image generated with ImageGen. A conceptual comparison of standardized test methods and documented nanomaterial results. Not actual premises, staff, meetings or decisions.
What this article covers
  1. The OECD in 30 seconds
  2. What kind of body it is: the four types of influence
  3. What it does for nanotechnology
  4. How far its influence reaches (powers and geography)
  5. How mutual acceptance of data works, and Decision versus Recommendation
  6. Outlook
  7. Glossary, references and claim-to-source audit

1. The OECD in 30 seconds

FULL NAMEOrganisation for Economic Co-operation and DevelopmentNanotechnology is handled by its Working Party on Manufactured Nanomaterials (WPMN)
COUNTRY / REGIONInternational (Paris, France)Headquartered in Paris. 38 member countries; the European Union also takes part in its work
TYPE OF BODYIntergovernmental organisationGovernment representatives agree on standards and recommendations. It does not dispense grants or loans
ESTABLISHEDOECD 1961 / WPMN active since 2006The WPMN has worked since 2006, according to OECD reports
SCALE (PEOPLE)More than 3,500 Secretariat staff38 member countries. The number of WPMN delegates could not be confirmed
SCALE (BODIES)More than 300 committees and bodiesAn OECD-wide figure. Funding comes from member contributions and voluntary contributions
ROLE IN NANOTECHNOLOGYTest-method standards and assessment guidanceTest Guidelines, guidance documents and a 2013 Council Recommendation
REACHMAD participantsThe 38 members plus seven non-member countries that are full adherents to MAD
The one point to grasp first

The OECD has Decisions, which can be legally binding, and Recommendations, which are not. The OECD itself explains that a Decision is legally binding on all Members except those that abstained when it was adopted, while a Recommendation is not legally binding and represents a political commitment, with an expectation that adherents will do their best to implement it Sourced. The Test Guidelines used for nanomaterials form part of the 1981 Council Decision on the Mutual Acceptance of Data, whose first part makes it binding on adherents to accept data generated under the stated conditions Sourced. The 2013 Council act that calls for adapting existing chemical regulation to the specific properties of manufactured nanomaterials, by contrast, is a Recommendation and has no binding force Sourced. Which tests are required, and how results are judged, is decided by each country's own regulation.

2. What kind of body it is: the four types of influence

The institutions that appear in nanotechnology coverage do not make nanomaterials themselves, unlike companies. They can be grouped into four types by the route through which they influence the field.

Four types of institution that shape nanotechnology Institutions do not make nanomaterials themselves; they differ in how they influence the field Funding Policy & regulation Standards Convening Allocates R&D budgets Strategy, grants, law Terms, tests, guidance Hubs and joint research NNI / European Commission European Commission / FDA ISO / OECD / NIST NIMS / imec What to research What to allow or require How to name and measure Who researches with whom Reach: own budget Reach: own country/region Reach: where adopted Reach: participants OECD is the Standards type: it agrees test methods, but only part of its output binds Even within nanotechnology, how influence reaches industry differs sharply by type
Fig. 1 The four types of institution that shape nanotechnology, and where the OECD sits. The grouping is this article's own, and the institution names are examples drawn from this series Our calculation. The OECD says it does not dispense grants or loans (reference 4), so it is not placed under Funding.

3. What it does for nanotechnology

The OECD's nanomaterials work sits within its chemical safety and biosafety programme and is centred on the Working Party on Manufactured Nanomaterials (WPMN). An OECD report says the WPMN has worked since 2006 to ensure that existing risk assessment approaches are suitable and reliable for nanomaterials Sourced. The 2013 Recommendation states that several subsidiary bodies of the Chemicals and Biotechnology Committee (CBC, formerly the Chemicals Committee), including the WPMN, have been working to align the safety testing and assessment of nanomaterials with the methods used for traditional chemicals Sourced.

AreaWhat the OECD's official pages and publications show
Test Guidelines specific to nanomaterials TG 318, Dispersion Stability of Nanomaterials in Simulated Environmental Media: 9 October 2017, 32 pages
TG 124, Determination of the Volume Specific Surface Area of Manufactured Nanomaterials: 30 June 2022, 18 pages
TG 125, Nanomaterial Particle Size and Size Distribution of Nanomaterials: 4 July 2023, 71 pages; described as covering particles and fibres from 1 nm to 1000 nm
TG 126, Determination of the Hydrophobicity Index of Nanomaterials Through an Affinity Measurement: 4 July 2023, 19 pages
TG 127, Dustiness determination of materials containing nano-objects and their aggregates and agglomerates: date shown on the publication page 2 July 2026, 115 pages
TG 322, Determination of the Solubility and Dissolution Rate of Nanomaterials for Environmental Fate Assessment: date shown on the publication page 2 July 2026, 41 pages
Guidance documents and related materialGuidance Documents 317 (aquatic and sediment ecotoxicity testing of nanomaterials) and 318 (solubility and dissolution rate), and a guidance document on using TG 312 (leaching in soil columns) for nanomaterials. For human health effects, two existing Test Guidelines have been updated for nanomaterials
Publication seriesThe series "Safety of Manufactured Nanomaterials and other Advanced Materials" (the latest number on the OECD's list is No. 115). The OECD notes that the reports on that page are available only through its ONE Members and Partners platform
Safe and sustainable innovationThe Safe(r) and Sustainable Innovation Approach (SSIA), which the OECD proposes: combine safety and sustainability early in material design, and have regulators prepare in advance
Council RecommendationRecommendation of the Council on the Safety Testing and Assessment of Manufactured Nanomaterials (OECD/LEGAL/0400), adopted 19 September 2013. It recommends adapting existing chemical regulatory frameworks to the specific properties of manufactured nanomaterials

* Dates and page counts are as shown on the OECD's NANOMET page and the TG 127 and TG 322 publication pages. The dates for TG 127 and TG 322 are those shown on the publication pages and are not necessarily adoption dates.

A materials engineer's view: why test methods come first

The OECD explains that nanomaterials may have properties different from the same substance in bulk form, which is why internationally standardised test methods are needed Sourced. For a materials supplier, once physical-chemical test methods such as TG 125 (particle size) and TG 124 (volume specific surface area) are aligned internationally, the same sample's results can be presented to regulators in several countries with fewer disagreements about method. That is a statement about how to measure, however; the OECD does not decide which values are acceptable.

4. How far its influence reaches (powers and geography)

DimensionWhat the OECD hasWhat the OECD does not have
PowerThe Council adopts Decisions (legally binding on Members that did not abstain) and Recommendations (not binding). The Test Guidelines and the Good Laboratory Practice (GLP) principles are set within the Mutual Acceptance of Data (MAD) systemRegulation that applies directly to companies; power to authorise, ban or register nanomaterials; the legal definition of a nanomaterial (set by laws such as the EU's); grants or loans (the OECD says it makes none)
Geography38 member countries (the EU also takes part). MAD includes seven non-member full adherents: Argentina, Brazil, India, Malaysia, Singapore, South Africa and ThailandDirect influence on the laws of countries and regions outside MAD and the Recommendation
ScopeTest methods (guidelines), data quality (GLP), assessment guidance and international information sharingWhich tests are required and how results are judged (set by each country's regulation; even under MAD, the receiving country decides how to interpret results)
ScaleMore than 3,500 Secretariat staff and more than 300 committees and bodies (OECD-wide). Part of the nanomaterials work is supported by an EU-funded project, NANOMETThe number of WPMN delegates and the budget for nanomaterials work could not be confirmed on the official pages

5. How mutual acceptance of data works, and Decision versus Recommendation

The centre of the OECD's influence is Mutual Acceptance of Data (MAD). The Council Decision adopted on 12 May 1981 (OECD/LEGAL/0194, amended 6 September 2019) provides that data from chemical tests generated in accordance with the OECD Test Guidelines and the Principles of Good Laboratory Practice (GLP) are accepted by other adherents for assessment. Part one of the Decision is legally binding; part two is not, and recommends that adherents apply the Test Guidelines and GLP in their testing Sourced.

How mutual acceptance of data (MAD) works, and Decision versus Recommendation One test accepted by many countries rests on a Decision; applying it to nanomaterials is a Recommendation Testing facility Tests per OECD Test Guidelines and GLP principles e.g. TG 125 (particle size) National GLP monitoring Inspects test facilities The OECD evaluates the programme itself Other adherents' regulators Accept the data Interpretation of results is up to the receiving country Decision: Mutual Acceptance of Data (OECD/LEGAL/0194; adopted 12 May 1981, amended 6 Sep 2019) Part 1 (legally binding): data produced under the conditions above must be accepted by adherents Part 2 (not binding): recommends applying OECD Test Guidelines and GLP in testing Recommendation: nanomaterial safety testing and assessment (OECD/LEGAL/0400; 19 Sep 2013) Recommends adapting existing chemical regulation to nanomaterials. Not legally binding GLP = Good Laboratory Practice. Acceptance applies only within each country's monitoring-programme scope
Fig. 2 How MAD works, and where the OECD's two nanomaterials-related documents fit. This article drew the diagram from the OECD's MAD page, Council Decision OECD/LEGAL/0194 and Council Recommendation OECD/LEGAL/0400 Our calculation.

According to the OECD, data from another country are accepted under MAD only when all of the following hold Sourced.

  • The study was conducted according to the OECD Test Guidelines and the OECD Principles of GLP.
  • The test facility has been inspected by a national GLP compliance monitoring programme.
  • That national programme has been successfully evaluated by the OECD.

The OECD explains that the receiving country must accept the study but keeps the prerogative of interpreting the results. Acceptance is also required only where the product falls within the scope of the national GLP monitoring programme Sourced.

Decision versus Recommendation, for nanomaterials

- The Decision (OECD/LEGAL/0194) requires acceptance of test data. Test Guidelines written for nanomaterials are used within this system.
- The Recommendation (OECD/LEGAL/0400, adopted 19 September 2013) recommends that Members apply existing chemical regulatory frameworks, adapted to the specific properties of nanomaterials. It also recommends applying the Test Guidelines and GLP, updating the Test Guidelines, and making nanomaterial safety data public. It is not binding.
- Its background information records, from a 2019 report, that two non-members, Argentina and Brazil, had adhered to the Recommendation, and says the 2025 report finds it generally well implemented, with remaining gaps in exposure assessment, new approach methodologies and the evaluation of advanced and complex materials. The next report to the Council is scheduled for 2035 Sourced.

Organisations around it

The relationships that can be confirmed from OECD publications are these Sourced.

OrganisationRelationship that can be confirmed
European CommissionThe OECD's NANOMET page says an EU-funded three-year project, NANOMET, launched in May 2020, supports the OECD's work on nanomaterial test methods. The 2025 SSIA report names researchers of the Commission's Joint Research Centre (JRC) among the project co-leads. The OECD and the European Commission are both listed as liaisons of ISO/TC 229 (reference 19)
ISO (ISO/TC 229)ISO's committee page lists the OECD as a Category A liaison organisation of TC 229. In terms of roles, the OECD sets test guidelines while ISO publishes measurement and terminology standards (this article's reading)
UN chemical-safety bodies (IOMC)The Recommendation's background says it is disseminated in collaboration with the participating organisations of the Inter-Organisation Programme for the Sound Management of Chemicals (IOMC), including FAO, ILO, UNDP, UNEP, UNIDO, UNITAR, WHO and the World Bank. It also records, in the 2019 report, that the non-members Malaysia, Singapore, South Africa and Thailand take part in the WPMN's work
Industry associationsThe acknowledgements of the 2025 SSIA report list a representative of the Nanotechnology Industries Association (NIA) among the project co-leads. No companies could be confirmed from the official pages, so none are named here

6. Outlook

What can be readPrimary source behind itType
A new draft guidance document on determining nanomaterial concentrations in biological samples is out for public commentThe OECD's first commenting round, 2 October to 13 November 2026. The project entered the Test Guideline work plan in 2021 on a proposal from the United KingdomNot yet confirmed
The next implementation report on the Recommendation (OECD/LEGAL/0400) is scheduled for 2035The Recommendation's background information. Its Annex can be amended by the CBC (last amended in October 2023)Not yet confirmed
The scope of work is widening from manufactured nanomaterials to "advanced materials"The publication series is now titled "Safety of Manufactured Nanomaterials and other Advanced Materials", and the OECD published a working description of advanced materials in 2023. The 2025 report on the Recommendation also names the evaluation of advanced and complex materials as a gapInference
New nanomaterial Test Guidelines are likely to keep being addedTG 127 and TG 322 were published in 2026, and draft guidance documents are out for commentInference

7. Glossary

WPMN
The OECD's Working Party on Manufactured Nanomaterials, which advances international co-operation on nanomaterial safety testing and assessment.
MAD (Mutual Acceptance of Data)
A system under which data generated per the OECD Test Guidelines and GLP are accepted by participating countries.
GLP (Good Laboratory Practice)
OECD principles setting quality standards for how test facilities are organised, run and record their work.
Test Guideline (TG)
An OECD-defined method for testing the safety of chemicals. Part of the 1981 Council Decision on MAD.
Decision / Recommendation
Types of OECD Council act. A Decision is legally binding on Members that did not abstain; a Recommendation is not binding and expresses an expectation of implementation.
SSIA
The Safe(r) and Sustainable Innovation Approach: combining safety and sustainability early in innovation, with regulators preparing in advance.

8. References

  1. OECD About (founded 1961; overview of the organisation). https://www.oecd.org/en/about.html
  2. OECD Organisational structure (the Council, more than 300 committees and bodies, more than 3,500 Secretariat staff). https://www.oecd.org/en/about/organisational-structure.html
  3. OECD Members and partners (38 member countries; participation of the EU). https://www.oecd.org/en/about/members-partners.html
  4. OECD Budget (funded by member contributions and voluntary contributions; the OECD does not dispense grants or loans). https://www.oecd.org/en/about/budget.html
  5. OECD OECD Legal Instruments: About (Decisions are legally binding; Recommendations are not). https://legalinstruments.oecd.org/en/about
  6. OECD Decision of the Council concerning the Mutual Acceptance of Data in the Assessment of Chemicals (OECD/LEGAL/0194; adopted 12 May 1981, amended 6 September 2019; part one binding, part two not binding). https://legalinstruments.oecd.org/en/instruments/OECD-LEGAL-0194
  7. OECD Recommendation of the Council on the Safety Testing and Assessment of Manufactured Nanomaterials (OECD/LEGAL/0400; adopted 19 September 2013; background information, paragraphs I to IX and Annex). https://legalinstruments.oecd.org/public/doc/298/298.en.pdf
  8. OECD Nanomaterials and advanced materials (topic page; the need for standardised test methods). https://www.oecd.org/en/topics/nanomaterials-and-advanced-materials.html
  9. OECD NANOMET: Towards tailored safety testing methods for nanomaterials (dates and page counts of TG 318, 124, 125 and 126; guidance documents; EU funding). https://www.oecd.org/en/topics/sub-issues/testing-of-chemicals/nanomet.html
  10. OECD Guidelines for the Testing of Chemicals (Test Guidelines are an integral part of the MAD Decision; TG 127 and TG 322 published in 2026). https://www.oecd.org/en/topics/sub-issues/testing-of-chemicals/test-guidelines.html
  11. OECD The Mutual Acceptance of Data (MAD) System (participants, MAD criteria, scope of acceptance). https://www.oecd.org/en/topics/sub-issues/testing-of-chemicals/mutual-acceptance-of-data-system.html
  12. OECD Testing of chemicals (MAD participants: 38 members and seven non-member countries). https://www.oecd.org/en/topics/testing-of-chemicals.html
  13. OECD Test No. 127: Dustiness determination of materials containing nano-objects and their aggregates and agglomerates (115 pages; date shown on the page 2 July 2026). https://www.oecd.org/en/publications/test-no-127-dustiness-determination-of-materials-containing-nano-objects-and-their-aggregates-and-agglomerates_d862c720-en.html
  14. OECD Test No. 322: Determination of the Solubility and Dissolution Rate of Nanomaterials for Environmental Fate Assessment (41 pages; date shown on the page 2 July 2026). https://www.oecd.org/en/publications/test-no-322-determination-of-the-solubility-and-dissolution-rate-of-nanomaterials-for-environmental-fate-assessment_693e2680-en.html
  15. OECD First commenting round on the determination of concentrations of nanomaterials in biological samples for (eco)toxicity studies (public consultation, 2 October to 13 November 2026). https://www.oecd.org/en/events/public-consultations/2026/10/first-commenting-round-on-the-determination-of-concentrations-of-nanomaterials-in-biological-samples-for-ecotoxicity-studies.html
  16. OECD Publications on the Safety of Manufactured Nanomaterials and Advanced Materials (list of the series; latest is No. 115). https://www.oecd.org/en/topics/sub-issues/nanomaterials-and-advanced-materials/other-reports-on-the-safety-of-manufactured-nanomaterials-and-advanced-materials.html
  17. OECD Safe(r) and Sustainable Innovation Approach (SSIA): Nano-Enabled and other Emerging Materials. https://www.oecd.org/en/topics/sub-issues/nanomaterials-and-advanced-materials/safer-and-sustainable-innovation-approach-ssia-nano-enabled-and-other-emerging-materials.html
  18. OECD Safe and sustainable by design tools, integrative systems and platforms for nanomaterials and nano-enabled products (December 2025; WPMN active since 2006; co-lead affiliations; reference to the working description of advanced materials). https://www.oecd.org/content/dam/oecd/en/publications/reports/2025/12/safe-and-sustainable-by-design-tools-integrative-systems-and-platforms-for-nanomaterials-and-nano-enabled-products_6285c02d/e411a4b7-en.pdf
  19. ISO ISO/TC 229 Nanotechnologies (the OECD and the European Commission are listed among the liaison organisations). https://www.iso.org/committee/381983.html

9. Claim-to-source audit

Claim in the textTypeReference
OECD founded in 1961; more than 3,500 Secretariat staff; more than 300 committees and bodies; 38 members and EU participationSourcedReference 1 https://www.oecd.org/en/about.html
Reference 2 https://www.oecd.org/en/about/organisational-structure.html
Reference 3 https://www.oecd.org/en/about/members-partners.html
Funding comes from member contributions and voluntary contributions, and the OECD does not dispense grants or loansSourcedReference 4 https://www.oecd.org/en/about/budget.html
Decisions are legally binding and Recommendations are not (the OECD's explanation)SourcedReference 5 https://legalinstruments.oecd.org/en/about
The MAD Decision (OECD/LEGAL/0194): adoption and amendment dates, part one binding, part two not binding, and "the receiving country keeps the prerogative of interpreting results"SourcedReference 6 https://legalinstruments.oecd.org/en/instruments/OECD-LEGAL-0194
The 2013 Recommendation (OECD/LEGAL/0400): adoption date, content, Annex, the 2019 and 2025 implementation reports, next report in 2035, work of subsidiary bodies including the WPMN, and co-operation with IOMCSourcedReference 7 https://legalinstruments.oecd.org/public/doc/298/298.en.pdf
The OECD's description of its nanomaterials work and the need for standardised test methodsSourcedReference 8 https://www.oecd.org/en/topics/nanomaterials-and-advanced-materials.html
Dates and page counts of TG 318, 124, 125 and 126; guidance documents 317 and 318; EU funding of NANOMETSourcedReference 9 https://www.oecd.org/en/topics/sub-issues/testing-of-chemicals/nanomet.html
Test Guidelines as an integral part of the MAD Decision; TG 127 and TG 322 published in 2026SourcedReference 10 https://www.oecd.org/en/topics/sub-issues/testing-of-chemicals/test-guidelines.html
Reference 13 https://www.oecd.org/en/publications/test-no-127-dustiness-determination-of-materials-containing-nano-objects-and-their-aggregates-and-agglomerates_d862c720-en.html
Reference 14 https://www.oecd.org/en/publications/test-no-322-determination-of-the-solubility-and-dissolution-rate-of-nanomaterials-for-environmental-fate-assessment_693e2680-en.html
MAD criteria (Test Guidelines and GLP, facility inspection, OECD evaluation of the monitoring programme), scope of acceptance and participantsSourcedReference 11 https://www.oecd.org/en/topics/sub-issues/testing-of-chemicals/mutual-acceptance-of-data-system.html
Reference 12 https://www.oecd.org/en/topics/testing-of-chemicals.html
The draft guidance document on nanomaterial concentrations in biological samples and its public comment period (2 October to 13 November 2026)SourcedReference 15 https://www.oecd.org/en/events/public-consultations/2026/10/first-commenting-round-on-the-determination-of-concentrations-of-nanomaterials-in-biological-samples-for-ecotoxicity-studies.html
The publication series, SSIA, the WPMN's activity since 2006, the 2023 working description of advanced materials, and co-lead affiliationsSourcedReference 16 https://www.oecd.org/en/topics/sub-issues/nanomaterials-and-advanced-materials/other-reports-on-the-safety-of-manufactured-nanomaterials-and-advanced-materials.html
Reference 17 https://www.oecd.org/en/topics/sub-issues/nanomaterials-and-advanced-materials/safer-and-sustainable-innovation-approach-ssia-nano-enabled-and-other-emerging-materials.html
Reference 18 https://www.oecd.org/content/dam/oecd/en/publications/reports/2025/12/safe-and-sustainable-by-design-tools-integrative-systems-and-platforms-for-nanomaterials-and-nano-enabled-products_6285c02d/e411a4b7-en.pdf
The OECD and the European Commission listed as liaison organisations of ISO/TC 229SourcedReference 19 https://www.iso.org/committee/381983.html
The four types of institution, the diagram in Fig. 2, and the description of the OECD's and ISO's differing rolesOur calculationOur own classification and diagram, based on references 5 to 7, 10, 11 and 19
Number of WPMN delegates and the budget for nanomaterials workNot yet confirmedNot stated in references 1 to 18. This article does not estimate them
When the draft guidance document under comment will be finalised, and the next report on the Recommendation (2035)Not yet confirmedReference 15 https://www.oecd.org/en/events/public-consultations/2026/10/first-commenting-round-on-the-determination-of-concentrations-of-nanomaterials-in-biological-samples-for-ecotoxicity-studies.html
Reference 7 https://legalinstruments.oecd.org/public/doc/298/298.en.pdf
The two outlook points marked as inference in section 6InferenceThis article's reading of the titles and content in references 16, 18, 7, 10 and 15

Last updated 9 October 2026 / Troy Technical
Figures and document status come from the OECD's website and the OECD Legal Instruments compendium as shown on 9 October 2026. Items marked "Inference" are this article's reading of the primary sources.

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