Business Trends– category –
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Fatal Adverse Event Halts HuidaGene’s First-in-Human CRISPR Gene Therapy Trial for DMD
HuidaGene Therapeutics China Overview HuidaGene Therapeutics has reported a fatal serious adverse event (SAE) in the HG302-01 first-in-human trial of its investigational CRISPR-based gene-editing therapy, HG302, for Duchenne muscular dys... -
Peptide Therapeutics: Charting a Course to Oral Delivery Amidst a Surge in FDA Approvals
Stanford Medicine USA Overview The FDA has approved nearly 100 peptide therapeutics for conditions ranging from diabetes to multiple sclerosis, yet most require injection due to their susceptibility to gastrointestinal degradation. A rec... -
Lonza Capsugel Pioneers Dual-Layer Strategy for Oral GLP-1 Delivery, Shielding Peptides from Enzymatic Attack
Capsugel (Lonza) Switzerland Overview Lonza Capsugel has engineered a novel dual-layer protection strategy to enable oral delivery of GLP-1 peptides, circumventing the critical challenge of enzymatic degradation within the gastrointestin... -
Alector Advances ‘Brain Carrier’ Platform: Optimizing Brain Drug Delivery via Transferrin Receptor Targeting with Enhanced Safety
Alector USA Overview Alector recently announced significant progress with its proprietary Alector Brain Carrier (ABC) blood-brain barrier (BBB) platform, designed to substantially enhance the delivery of therapeutic agents to the brain. ... -
ReCode Therapeutics Secures Funding, Partners with Gene Editing Firm to Fast-Track Cystic Fibrosis Gene Therapy with SORT LNP Platform
BioSpace (via Business Wire) USA Overview ReCode Therapeutics has announced new funding from the Cystic Fibrosis Foundation and a strategic partnership with a leading gene editing company. These initiatives will accelerate the developmen... -
Eurofins CDMO Alphora Expands Kilolab and HPAPI Manufacturing, Strengthening Integrated ADC Development
Las Vegas Sun News (via Business Wire) USA Overview Eurofins CDMO Alphora has significantly expanded its kilolab and High Potency Active Pharmaceutical Ingredient (HPAPI) development and manufacturing capabilities at its Mississauga, Can... -
Peking University Unveils SynTar LNPs: A Precision Breakthrough for Targeted mRNA Lung Delivery
SINOPEG China Overview Researchers at Peking University have developed an innovative SynTar lipid nanoparticle (SynTar LNP) platform, overcoming a critical bottleneck in targeted mRNA delivery to the lungs. This system significantly enha... -
乳がん治療向け次世代ADCの開発課題と進歩：送達生物学の最適化が成功の鍵
PubMed (Expert Opinion on Drug Delivery) USA Overview Expert Opinion on Drug Deliveryに掲載されたレビューは、乳がんの治療抵抗性疾患に対する次世代抗体薬物複合体（ADC）の開発における進歩と課題を統合的に評価しました。本レビューは、ADCの設計... -
AI-Powered In Silico Design Revolutionizes RNA-LNP Therapies for Targeted Delivery and CRISPR Gene Editing
InSilicoMinds USA Overview In silico (computational) design is fundamentally transforming the development of lipid nanoparticle (LNP) and RNA therapeutics by enabling the precise optimization of LNP properties for tissue-specific drug de... -
Entera Bio’s Oral Peptide Platform Advances to Phase 3 for Osteoporosis, Heralding a New Era for Injectable Therapeutics
Entera Bio, Inc. USA Overview Clinical-stage biopharmaceutical company Entera Bio has secured an agreement with the FDA to initiate a Phase 3 clinical trial for EB613, an oral parathyroid hormone (PTH) analog for postmenopausal osteoporo...
