Drug Discovery & DDS– category –
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Ribo Life Science’s siRNA Therapy Vortosiran Receives EMA Approval for Stroke Prevention Trial in Atrial Fibrillation Patients
Insight, China's Pharmaceutical Industry China Overview Ribo Life Science's siRNA therapy, vortosiran (BD4059), has received clinical trial approval from the EMA for stroke prevention in atrial fibrillation (SPAF) patients. Vortosiran is... -
First Half 2026 Sees 24 New Small-Molecule Approvals: Pioneering PROTAC Vepdegestrant and Oral GLP-1 Orforglipron Enter Market
Chemexpress China Overview Twenty-four small-molecule drugs received their first global approval in the first half of 2026, with 95.8% being oral dosage forms. Key highlights include the approval of the first commercial PROTAC, vepdegest... -
Daiichi Sankyo & AstraZeneca’s Enhertu Plus Pertuzumab Recommended for EU Approval as 1st-Line Treatment for HER2-Positive Metastatic Breast Cancer, Achieves 44% Risk Reduction in Phase III
Daiichi Sankyo Press Release Japan Overview The EMA's CHMP has recommended Enhertu (trastuzumab deruxtecan) in combination with pertuzumab for approval as a first-line treatment for HER2-positive metastatic breast cancer in the EU. This ... -
Insilico Medicine’s AI-Driven Pan-TEAD Inhibitor ISM6331 Receives FDA Fast Track Designation for Advanced Mesothelioma, Accelerating Development
Insilico Medicine Press Release USA Overview Insilico Medicine announced that its AI-driven pan-TEAD inhibitor, ISM6331, developed using the Chemistry42 platform, received Fast Track Designation from the FDA for advanced malignant pleura... -
EMA CHMP Recommends 12 Medicines for Approval, Including 3 New Hypercholesterolemia Drugs and Therapies for Cholestatic Pruritus and Cerebral Adrenoleukodystrophy
EMA EU Overview The EMA's Committee for Medicinal Products for Human Use (CHMP) adopted positive opinions for twelve medicines at its July 2026 meeting. This includes three new medicines for hypercholesterolemia or mixed dyslipidemia: Ly... -
Eli Lilly’s Retatrutide Emerges as Most Powerful Obesity Drug Yet, Achieves Five Consecutive Positive Phase 3 Readouts in TRIUMPH Program
Drug Discovery News USA Overview Eli Lilly's triple agonist retatrutide has shown positive results in metabolic disease, positioning it as a powerful obesity drug. The company has achieved five consecutive positive Phase 3 readouts acros... -
LNP-Mediated Gene Therapy to Correct ACTA2 Mutations Shows Promise: Reduces Stroke-Related Mortality, Offers Re-dosability & Lower Costs Over Viral Vectors
MSMDS.org USA Overview A novel lipid nanoparticle (LNP)-based gene therapy strategy is under development to correct ACTA2 mutations in vascular smooth muscle cells. This approach offers significant advantages over viral vectors, includin... -
Daiichi Sankyo’s Early ADC Pipeline Lags Rivals as Cash Flow Nears Peak, Incurs $850M Charges for Underutilized CMO Capacity
BioSpace USA Overview Jefferies analysts suggest Daiichi Sankyo's early-stage antibody-drug conjugate (ADC) pipeline is not keeping pace with rivals, despite the success of Enhertu and Datroway. Enhertu and Datroway are nearing peak reve... -
Complete Guide to Lipid Nanoparticles (LNP): Foundational Technology for Nucleic Acid Delivery Validated by mRNA Vaccine Success
Inside Therapeutics USA Overview Lipid nanoparticles (LNPs) are nanoscale delivery vehicles designed to protect and deliver nucleic acids like mRNA and siRNA into cells, serving as the delivery platform for COVID-19 mRNA vaccines. LNPs o... -
Biopharmaceuticals Contract Manufacturing Market Expands Amid Global Demand: CDMOs Scale Up Capacity
openPR.com Unknown Overview This article provides an overview of a market research report published by openPR.com. The biopharmaceutical contract manufacturing market is growing due to increased demand for biosimilars, expanded investmen...
