Agonist– tag –
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Eli Lilly’s Oral GLP-1 Agonist ‘Foundayo (orforglipron)’ Receives FDA Approval for Obesity and Overweight Treatment
Drugs.com USA Overview Eli Lilly's Foundayo (orforglipron), a once-daily oral GLP-1 receptor agonist, has received FDA approval for adults with obesity or certain weight-related conditions. This small-molecule, non-peptide GLP-1 receptor... -
Oral GLP-1 Market Soars: Eli Lilly’s Foundayo and Novo Nordisk’s Oral Wegovy Reach New Prescription Highs
Fierce Pharma USA Overview Weekly prescriptions for Eli Lilly's oral GLP-1 agonist Foundayo and Novo Nordisk's oral Wegovy have reached new highs, demonstrating the significant impact of oral GLP-1 drugs on the obesity treatment landscap... -
GLP-1 Agonist Tirzepatide Significantly Reduces Cardiovascular Events and Infection Risk by One-Third in Type 2 Diabetes and Obesity Patients
Technical University of Munich Germany Overview A study published in The BMJ, conducted by researchers from the Technical University of Munich and Harvard Medical School, found that tirzepatide (Mounjaro), a GLP-1 agonist, significantly ... -
China’s Ascletis Initiates Global Phase III for Oral GLP-1 Obesity Drug ASC30, Preclinical Triple Agonist FDC Shows Strong Weight Reduction
Ascletis (via news release) China Overview Chinese company Ascletis has initiated a global Phase III trial for its oral GLP-1 obesity drug, ASC30. Concurrently, the company announced positive preclinical data for its first-in-class, once... -
Boehringer Ingelheim Initiates Phase II for BI 3034701, a Novel GLP-1/GIP/NPY2 Triple Agonist, Reshaping Obesity Treatment
Life Science Daily News USA Overview Boehringer Ingelheim initiated a Phase II trial in July 2026 for BI 3034701 (NCT07662122), a groundbreaking triple agonist targeting GLP-1, GIP, and the NPY2 receptor, signaling a new direction beyond... -
GLP-1 Review Finds Strongest Signals for GI Adverse Events, Hints at Reduced Infection/Respiratory Risk
GI and Hepatology News USA Overview A systematic review and meta-analysis published in JAMA Network Open found that GLP-1 receptor agonists (GLP-1 RAs) consistently increase gastrointestinal side effects like nausea, vomiting, and diarrh... -
Semaglutide More Than Doubles MASH Resolution Likelihood in Meta-Analysis, Stabilizing Fibrosis
AJMC USA Overview A systematic review and meta-analysis published in Medicine reveals that the GLP-1 receptor agonist semaglutide more than doubles the likelihood of MASH (metabolic dysfunction-associated steatohepatitis) resolution with... -
GLP-1 Receptor Agonist Research Rapidly Expanding Across MASLD–MASH–HCC Continuum: US Leads, China Shows Rapid Growth
Frontiers Switzerland Overview Research on GLP-1 Receptor Agonists (GLP-1RAs) in the context of MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease), MASH (Metabolic Dysfunction-Associated Steatohepatitis), and HCC (Hepatocel... -
Oral GLP-1 Drugs May Quash Brain’s Food Craving Circuit, NIH-Funded Study Suggests Role in Hedonic Eating and Addiction
ScienceDaily USA Overview A study funded by the NIH suggests that newer oral small-molecule GLP-1 drugs, such as orforglipron and danuglipron, may reduce hedonic feeding (eating for pleasure) by affecting a reward circuit in the brain. T... -
First Half 2026 Sees 24 New Small-Molecule Approvals: Pioneering PROTAC Vepdegestrant and Oral GLP-1 Orforglipron Enter Market
Chemexpress China Overview Twenty-four small-molecule drugs received their first global approval in the first half of 2026, with 95.8% being oral dosage forms. Key highlights include the approval of the first commercial PROTAC, vepdegest...
