Agonist– tag –
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Drug Discovery & DDS
Eli Lilly’s Retatrutide Emerges as Most Powerful Obesity Drug Yet, Achieves Five Consecutive Positive Phase 3 Readouts in TRIUMPH Program
Drug Discovery News USA Overview Eli Lilly's triple agonist retatrutide has shown positive results in metabolic disease, positioning it as a powerful obesity drug. The company has achieved five consecutive positive Phase 3 readouts acros... -
New Technology
Eli Lilly’s Triple Agonist Retatrutide Achieves 21-23% Weight Loss in Diabetic and CVD Patients Over 80 Weeks, Nears FDA Submission
BioPharma Dive USA Overview Eli Lilly is preparing to seek FDA approval for its obesity drug retatrutide, a triple agonist targeting GLP-1, GIP, and glucagon receptors. New data from the Triumph-2 and Triumph-3 studies showed average bod... -
Drug Discovery & DDS
Eli Lilly’s Triple G-Agonist Retatrutide Succeeds in Two More Phase III Trials for Obesity and Type 2 Diabetes
GlobalData USA Overview Eli Lilly's GLP-1/GIP/Glucagon (GCG) triple receptor agonist, retatrutide, met primary endpoints in two additional Phase III trials (TRIUMPH-2 and TRIUMPH-3) for type 2 diabetes and obesity patients with establish... -
New Technology
Boehringer Ingelheim Initiates Phase II Trial for BI 3034701, a Potential First-in-Class Triple Receptor Agonist for Obesity
Boehringer Ingelheim Germany Overview Boehringer Ingelheim has launched a Phase II clinical trial for BI 3034701, an investigational triple GLP-1/GIP/NPY2 receptor agonist targeting patients with obesity and overweight. This molecule rep... -
Market Trends
Oral GLP-1 Market Shift: Foundayo (orforglipron) Gains FDA Approval After Oral Wegovy, Demonstrating Dosing Convenience Advantage
GoodRx Health USA Overview The oral GLP-1 receptor agonist market sees a new entrant as Foundayo (orforglipron) received FDA approval on April 1, 2026, becoming the second oral GLP-1 therapy after oral Wegovy (semaglutide). Foundayo offe... -
Drug Discovery & DDS
Obesity Treatment Advances: Foundayo and Oral Wegovy Lead Oral GLP-1 Market, Retatrutide Shows Significant Weight Loss in Phase II
GoodRx Health USA Overview The obesity therapeutics market is rapidly evolving, with Foundayo (orforglipron) and oral Wegovy driving the oral GLP-1 segment. Foundayo, FDA-approved on April 1, 2026, offers the novel advantage of being tak... -
New Technology
Boehringer Ingelheim’s First-in-Class Obesity Drug BI 3034701 Enters Phase II, Triggers €10M Milestone Payment to Gubra
Boehringer Ingelheim Germany Overview Boehringer Ingelheim has initiated a Phase II clinical trial for BI 3034701, a potential first-in-class GLP-1/GIP/NPY2 triple receptor agonist for patients with obesity and overweight. This investiga... -
Market Trends
Eli Lilly’s Foundayo (orforglipron) Receives FDA Approval, Ushering in a New Era of Oral GLP-1 RAs for Obesity Treatment
2 Minute Medicine USA Overview On April 1, 2026, Eli Lilly's Foundayo (orforglipron) gained FDA approval for obesity treatment, marking the first non-peptide oral GLP-1 receptor agonist without food or water timing restrictions. This bre... -
New Technology
Boehringer Ingelheim Announces Promising Interim Phase 2 Results for Obesity Treatment BI 3034701: A Potential First-in-Class Triple Receptor Agonist
Boehringer Ingelheim Germany Overview Boehringer Ingelheim announced promising interim results from its Phase 2 clinical trial for BI 3034701, a novel triple receptor agonist for obesity. BI 3034701, targeting GLP-1, GCG, and GIP recepto... -
New Technology
2026 GLP-1 Agonist Pipeline Highlights Oral Orforglipron Approval and Retatrutide’s >28% Weight Reduction
Drug Discovery News USA Overview The 2026 GLP-1 agonist clinical pipeline is focusing on enhanced weight loss efficacy through novel mechanisms. Notably, Eli Lilly's oral small-molecule GLP-1 receptor agonist, orforglipron, received FDA ...