Lipid Nanoparticle– tag –
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Drug Discovery & DDS
UBC-Led Global Review Reaffirms mRNA Vaccine Safety & Efficacy, Accelerating Applications in Cancer and Beyond
UBC News - The University of British Columbia Canada Overview An extensive global review led by researchers at the University of British Columbia has unequivocally reaffirmed the safety and efficacy of COVID-19 mRNA vaccines. Based on bi... -
Drug Discovery & DDS
COVID-19 mRNA Vaccines Comprehensively Proven Safe and Effective, Establishing Foundation for Future mRNA Therapeutics
CIDRAP (Center for Infectious Disease Research and Policy) USA Overview Extensive real-world use and rigorous evaluation of COVID-19 mRNA vaccines have conclusively demonstrated their comprehensive safety and efficacy, establishing a rob... -
New Technology
Patisiran and Inotersen Halt Polyneuropathy Progression in hATTR Amyloidosis; Next-Gen siRNA Vutrisiran Also FDA Approved
oneAMYLOIDOSISvoice USA Overview Patisiran (Onpattro) and inotersen (Tegsedi), TTR mRNA silencing therapies for hereditary ATTR amyloidosis (hATTR), have demonstrated the ability to halt the progression of polyneuropathy and even show im... -
Drug Discovery & DDS
Focused Ultrasound BBB Opening Facilitates Limited LNP-modRNA Brain Delivery in Niemann-Pick Disease Type C Mouse Model but Fails to Induce Therapeutic Effect
bioRxiv Unknown Overview Efficient molecular therapeutic delivery to the central nervous system (CNS) remains a major barrier in neurogenetic disorders like Niemann-Pick Disease Type C (NPC). This preprint evaluated Focused ultrasound-me... -
Nanotechnology
Diversa Technologies Develops Biodegradable Lipid Nanoparticle Platform for Protein Replacement Therapy, Accelerating Next-Gen Therapeutic Development
Diversa Technologies USA Overview Diversa Technologies is developing advanced nanomedicine platforms based on biodegradable lipid nanoparticles for targeted and controlled delivery of therapeutic modalities like mRNA and proteins, accele... -
Nanotechnology
Big Pharma’s Nanotech Bet: Pfizer, Moderna, AstraZeneca Spearhead LNP Drug Delivery Revolution, Says DataM Intelligence
DataM Intelligence International Overview A new market research report from DataM Intelligence highlights the leading companies shaping the nanotechnology drug delivery landscape. The study reveals that pharmaceutical and biotechnology g... -
Nanotechnology
MDPI Review Highlights Lipid Nanoparticles (LNPs) as Key to Rapid Antiviral Strategies for Pandemic Preparedness
MDPI International Overview A new MDPI review elaborates on nanoparticle-mediated antiviral strategies, emphasizing lipid nanoparticle (LNP) systems for their rapid response and efficient nucleic acid delivery in pandemic preparedness. N... -
Nanotechnology
Albumin-Hitchhiking Lipid Nanoparticles Achieve 80% Liver Accumulation Reduction and 2-3x Lymphatic mRNA Expression
ACS Materials Au USA Overview A novel lipid nanoparticle (LNP) delivery concept has been developed to overcome the off-target liver accumulation and associated hepatotoxicity of mRNA therapeutics by interacting with endogenous albumin. T... -
Nanotechnology
Cytiva Advances In Vivo CAR-T Therapy with Targeted mRNA-LNP Delivery to the Spleen
Cytiva スウェーデン Overview Cytiva is making significant strides in *in vivo* CAR-T therapy by utilizing advanced lipid nanoparticle (LNP) systems for direct T cell reprogramming within patients. This innovative approach extends LNP del... -
New Technology
Labcorp Strengthens Lipid Nanoparticle (LNP) Development as Non-Viral Vectors for Vaccine and Cell/Gene Therapy
Labcorp USA Overview Labcorp is emphasizing the crucial role of lipid nanoparticles (LNPs) as effective non-viral vectors for nucleic acid delivery in vaccines, cancer therapies, and cell and gene therapies. A key industry challenge is d...