Lipid Nanoparticle– tag –
-
Cartesian Therapeutics Licenses WestGene LNP Technology, Initiates Phase 1 for In Vivo CAR-T Descartes-08 in Myasthenia Gravis, Streamlining Manufacturing
Biospace USA Overview Cartesian Therapeutics announced a strategic licensing agreement with WestGene Biopharma to accelerate its in vivo CAR-T platform development using WestGene’s targeted lipid nanoparticle (LNP) technology. This colla... -
Moderna-Merck Cancer Vaccine Enters Phase 3, mRNA Therapeutics LNP Manufacturing Scales Beyond 17 L/hr, Rare Metabolic Disease Drugs Nearing Approval Studies
BioProcess International USA Overview Six key developments are shaping mRNA therapeutics beyond COVID-19 vaccines: Moderna and Merck's personalized cancer vaccine has advanced to Phase 3 trials, and rare metabolic disease drugs like mRNA... -
Samsung Biologics Secures Multi-Year mRNA Vaccine CDMO Partnership with Major Pharma, Leading Market Expansion
Business Korea South Korea Overview Samsung Biologics has reportedly secured a multi-year contract for large-scale mRNA vaccine manufacturing with a global pharmaceutical company. This new partnership further solidifies Samsung Biologics... -
Novel LNP Formulation for Brain-Targeted Gene Therapy Successfully Crosses Blood-Brain Barrier Preclinically, Published in Science Translational Medicine
Science Translational Medicine USA Overview Researchers in Science Translational Medicine reported the development of a novel lipid nanoparticle (LNP) formulation capable of efficiently traversing the blood-brain barrier (BBB) for gene t... -
Novel LNP Formulation Significantly Enhances Extra-hepatic mRNA Delivery to Lung Tissue, Published in Nature Communications
Nature Communications Unknown Overview A groundbreaking study in Nature Communications reports a novel lipid nanoparticle (LNP) formulation that significantly enhances extra-hepatic delivery of mRNA specifically to lung tissue. This adva... -
Comprehensive Review Spotlights Lipid Nanoparticles as a Transformative Drug Delivery System
International Journal of Scientific Research and Technology (Int. J. Sci. R. Tech.) India Overview The International Journal of Scientific Research and Technology has published a detailed review positioning lipid nanoparticles (LNPs) as ... -
AI/ML Frameworks Drive Rapid Optimization of Lipid Nanoparticle Formulations for Advanced Drug Delivery
Frontiers Switzerland Overview Lipid Nanoparticles (LNPs) are a cornerstone for advanced drug and nucleic acid delivery, yet their rational design presents a formidable multivariate challenge. New research harnesses AI/Machine Learning (... -
mRNA-LNP: The Non-Viral Platform Revolutionizing In Vivo CAR-T Cell Engineering
Journal of Controlled Release Unknown Overview The convergence of messenger RNA (mRNA) and lipid nanoparticle (LNP) delivery technology is poised to transform in vivo CAR-T cell engineering. This non-viral platform promises significant a... -
Lonza Pioneers Adaptive Manufacturing for In Vivo mRNA-LNP Therapies, Unlocking CRISPR for Rare Diseases and Cancer Immunotherapy
BioXconomy Switzerland Overview Lonza has unveiled an adaptive manufacturing platform designed to accelerate the development and production of in vivo mRNA-lipid nanoparticle (LNP) delivery systems. This breakthrough technology promises ... -
Beyond LNPs: Polymer Delivery Systems Promise Enhanced Stability, Reduced Toxicity, and Targeted Delivery for mRNA Therapeutics
MDPI Switzerland Overview Polymer-based delivery systems are rapidly emerging as a promising alternative to conventional lipid nanoparticles (LNPs) for mRNA therapeutics. While LNPs have achieved significant clinical success, particularl...
