off-the-shelf– tag –
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REPROCELL Develops Hypoimmune iPSC Engineering with AI-Designed CRISPR for Off-the-Shelf Cell Therapies
REPROCELL Japan Overview REPROCELL announced a method to develop hypoimmune iPSCs using AI-designed CRISPR, leveraging its StemEdit gene-editing platform. This approach targets key immune recognition genes like B2M and CIITA to create un... -
ENCell Secures US Clinical Manufacturing Contract for Ingenium Therapeutics’ NK Cell Therapy Gengleucel, Expanding Global CDMO Operations
Bio South Korea Overview ENCell, a South Korean CDMO specializing in cell and gene therapy, has signed an additional CMO contract with Ingenium Therapeutics for the manufacturing of clinical trial materials for its NK cell therapy candid... -
Allogeneic BCMA CAR T Therapy CB-011 Achieves Deep Responses and Confirms Immune Cloaking in Multiple Myeloma Phase 1 Trial
The ASCO Post USA Overview CB-011, the first allogeneic anti-BCMA CAR T-cell therapy incorporating immune cloaking technology, achieved a high overall response rate (ORR) in its Phase 1 CaMMouflage trial for relapsed/refractory heavily p... -
Caribou Biosciences’ Off-the-Shelf Allogeneic CAR T Vispa-cel Shows Superior PFS to Approved Autologous CAR T Therapies in Lymphoma Phase 1
Fierce Biotech USA Overview Caribou Biosciences announced promising median progression-free survival (PFS) data from its Phase 1 clinical trial of vispacabtagene regedleucel (vispa-cel), an off-the-shelf allogeneic CAR T-cell therapy for... -
Imviva Biotech’s Off-the-Shelf Allogeneic CAR T Therapy CTD402 Achieves High Response Rates in Relapsed/Refractory T-ALL/LBL at EHA Presentation
GlobeNewswire (Imviva Biotech) USA Overview Imviva Biotech presented promising clinical data for its next-generation off-the-shelf allogeneic CAR T-cell therapy, CTD402, at the EHA 2026 annual meeting. The therapy targets adult and pedia... -
Fate Therapeutics Presents Positive Clinical and Preclinical Data for iPSC-Derived Off-the-Shelf CAR T Therapies FT819, FT839, and FT836 in Autoimmune Diseases and Solid Tumors
Fate Therapeutics USA Overview Fate Therapeutics unveiled updated clinical and preclinical data for its iPSC-derived off-the-shelf CAR T-cell programs at EULAR and in corporate presentations. The Phase 1 trial for anti-CD19 CAR T-cell th... -
Cellectis’ Lasme-cel Receives FDA RMAT Designation as First Allogeneic CAR T in Pivotal Trial for R/R B-ALL, EHA Data Confirms Efficacy
Stock Titan (Cellectis SEC Filing) USA Overview Cellectis announced that its CD22-targeting allogeneic CAR T-cell therapy candidate, lasme-cel (UCART22), has received Regenerative Medicine Advanced Therapy (RMAT) designation from the FDA... -
Sana Biotechnology to Initiate Hypoimmune Cell Therapy and In Vivo CAR T Trials This Year, with Data Expected Within 12 Months
TradingView USA Overview Sana Biotechnology is set to commence clinical trials for two key platforms this year: a hypoimmune cell therapy targeting Type 1 diabetes and an in vivo CAR T platform for oncology and autoimmune diseases. Initi... -
Made Scientific and Pluristyx Announce Integrated iPSC Development & Manufacturing Partnership to Accelerate Next-Generation iPSC-Derived Cell Therapies
PR Newswire USA Overview Made Scientific, a cell therapy CDMO, and Pluristyx, an iPSC platform technology provider, announced an integrated iPSC development and manufacturing partnership. This collaboration aims to accelerate the clinica... -
Fate Therapeutics Presents FT819/FT839 Data at EULAR 2026: Rapid, Sustained Improvement and Favorable Safety Profile in SLE Patients
GlobeNewswire (Fate Therapeutics Press Release) USA Overview Fate Therapeutics presented data from its off-the-shelf CAR T-cell programs, FT819 and FT839, at the 2026 European Congress of Rheumatology (EULAR) Annual Meeting. FT819 demons...
