Process Analytical Technology– tag –
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arXiv Paper: Raman Data Fusion & ML Improve Cell Culture Process Forecasting Accuracy
arXiv USA Overview A new arXiv paper introduces a multipath adaptive gated bottleneck latent ODE with Raman data fusion, significantly improving cell culture process forecasting accuracy, evaluated on fed-batch 5L bioreactor runs. The re... -
Hyperspectral.ai Bridges Bioprocess Visibility Gap with Raman Chemometrics for Real-Time PAT
Hyperspectral.ai USA Overview Hyperspectral.ai has unveiled a technology that enables real-time, non-invasive monitoring of mammalian cell culture processes by combining Raman spectroscopy with chemometric and machine learning models. Th... -
Real-Time Fermentation Monitoring Achieved with Raman Spectroscopy-Based PAT in Food, Beverage & Industrial Bioprocessing
Technology Networks Global Overview Process Analytical Technology (PAT) tools, particularly Raman and Near-Infrared (NIR) spectroscopy, are extending their application from biopharma bioreactors to industrial fermentation for real-time m... -
arXiv Paper: Raman Data Fusion with Latent ODE Enhances Cell Culture Process Forecasting Accuracy
arXiv (Preprint) Global Overview New research published on arXiv proposes an innovative approach to improve cell culture process forecasting accuracy by fusing Raman spectroscopy data with a 'Multipath Adaptive Gated Bottleneck Latent OD... -
In-Line Sensors Play Crucial Role in Single-Use Biomanufacturing, Driving PAT Adoption and Enhancing Process Control
Technology Networks Global Overview In-line sensors are proving indispensable in single-use biomanufacturing for improving process efficiency and reliability. Directly integrated into single-use bioreactor bags, these sensors enable cont... -
Bioprocessing Technologies Reshape Food Production, Environmental Applications, and Sustainable Manufacturing Beyond Pharma
Technology Networks Global Overview Bioprocessing technologies are redefining various industries beyond pharmaceuticals, including food production, environmental applications, and sustainable manufacturing. Key technologies like fermenta... -
Lonza’s OptiALTO™ Platform Leverages Raman Spectroscopy as PAT to Significantly Boost High-Cell-Density Culture Productivity
Lonza Switzerland Overview Lonza's OptiALTO™ platform is achieving significant increases in productivity for high-cell-density cultures by integrating Raman spectroscopy as a Process Analytical Technology (PAT). This innovative approach ... -
Raman Spectroscopy Emerges as Key PAT for Real-time Metabolite Monitoring in Continuous & Perfusion Bioprocessing, Aligned with ICH Q13 Guidelines
Technology Networks Global Overview Process Analytical Technology (PAT) strategies are increasingly crucial for optimizing continuous and perfusion bioprocessing. Raman spectroscopy is emerging as the preferred in-line analytical techniq... -
Digital Biomanufacturing Market Projected to Reach $66.14 Billion by 2034, Driven by Automation and AI: Market Research Report
Fortune Business Insights Global Overview This article summarizes a Digital Biomanufacturing Market research report from Fortune Business Insights. The report projects the digital biomanufacturing market will reach $66.14 billion by 2034... -
Real-Time Monitoring Tools Advance Bioreactor Scale-Up, Integrating Digital Twins and PAT for Enhanced Efficiency
Cellbase Global Overview To efficiently scale up bioreactors, real-time monitoring tools—including electrochemical and optical sensors, PAT instruments like Raman and NIR spectroscopy, and capacitance probes for live cell density—are rap...
