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Isomorphic Labs Advances AI-Designed Oncology and Immunology Therapeutics to Clinical Trials Leveraging AlphaFold 3
IntuitionLabs UK Overview Isomorphic Labs is advancing its first computationally designed oncology and immunology therapeutics into clinical trials, leveraging AlphaFold-derived AI models, including AlphaFold 3. The company aims to drast... -
Protai Introduces Structural-Proteomics-Guided AI ‘AIMS-Fold’ to Revolutionize Induced Proximity Drug Design
BioSpace USA Overview Protai announced two preprints introducing AIMS-Fold, a structural-proteomics-guided generative AI framework for protein complex modeling, specifically for induced proximity therapeutics like PROTACs and molecular g... -
MDPI Highlights AI Drug Discovery’s Clinical Impact Deficit and Validation Crisis: AlphaFold’s Limitations and Regulatory Challenges
MDPI Switzerland Overview A review article by MDPI discusses the current state of AI in drug discovery (2022-2026), noting significant investment and accelerated early-stage discovery timelines but highlighting limited validated clinical... -
AI/Machine Learning Drives Target Identification and Precision Nanomedicine in Drug Discovery, Enhancing Candidate Selection and Pathway Analysis
Dove Medical Press USA Overview Machine learning (ML) and deep learning (DL) strategies are advancing drug discovery by enhancing target identification and precision nanomedicine. These technologies leverage virtual screening and bioacti... -
Integrating AI and Nodal Biology Accelerates Cell Response Prediction, Building Future Drug Discovery Engine
amacad.org USA Overview The integration of artificial intelligence with "nodal biology" is poised to revolutionize drug discovery by accelerating target identification through predicting human cellular responses to disease perturbations.... -
AlphaFold and AlphaFold 3 Revolutionize Protein Structure and Interaction Prediction, Significantly Accelerating Drug Discovery
IntuitionLabs / dev.to USA Overview AlphaFold and its successor, AlphaFold 3, are dramatically advancing protein structure and molecular interaction prediction, significantly compressing traditional drug discovery timelines. AlphaFold 3 ... -
ACS Sensors Demonstrates Modular Biosensor Design with De Novo Protein Switch ‘LOCKR’ for Troponin I and HBV Antibody Detection
ACS Sensors USA Overview A study in ACS Sensors introduces a modular input-output biosensor design utilizing the de novo protein switch platform, LOCKR. This platform enables direct conversion of target binding events into specific signa... -
Fujifilm Diosynth Biotechnologies Strengthens Technological Leadership in Cell Culture, Microbial Fermentation, Viral Vectors, and Cell Therapy Manufacturing
MabDesign France Overview Fujifilm Diosynth Biotechnologies is focused on combining its technological leadership with cGMP manufacturing facilities across key areas: cell culture, microbial fermentation, viral vectors, and cell therapy. ... -
Université Laval Announces Research Project on Predictive Modeling for Biomanufacturing Processes
Université Laval Canada Overview Université Laval has announced a research project focused on predictive modeling of biomanufacturing processes. Key themes include digital twins, machine learning, cell culture, proteins, bioreactors, and... -
AGC Biologics Secures CDMO Contract with Teikoku Seiyaku for Recombinant rhMMP-7 Drug Substance, GMP Production at Chiba Plant
AGC Biologics Japan Overview AGC Biologics has signed a CDMO contract with Teikoku Seiyaku Co. for the microbial drug substance manufacturing of recombinant human matrix metalloproteinase-7 (rhMMP-7) 'KTP-001'. Initial cell bank creation...
