Screening– tag –
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AI-Enabled Assay Discovers 31 Anti-Aging Compounds from 2,782 FDA-Approved Drugs, Extending C. elegans Lifespan
bioRxiv International Overview A bioRxiv preprint describes an open-source AI-enabled screening platform using C. elegans to rapidly identify geroprotective drugs. The platform screened 2,782 FDA-approved compounds, identifying 31 agents... -
Integrated LNP Composition and Ligand Targeting Dramatically Enhances Pancreatic Beta Cell-Directed RNA Delivery
ACS Nano USA Overview Engineering lipid nanoparticles (LNPs) through integrated compositional and ligand targeting dramatically enhances pancreatic beta cell-directed RNA delivery. Systematically varying the species and molar ratios of t... -
ACE Therapeutics’ LNP Gene Editing Platform Achieves Over 90% Hepatocyte Selectivity for Lipoprotein-Targeted Cardiovascular Therapeutics
ACE Therapeutics USA Overview ACE Therapeutics' LNP-delivered gene editing platform achieves over 90% efficient hepatocyte-selective delivery for lipoprotein-targeted cardiovascular therapeutics, minimizing extrahepatic editing risks. Th... -
Generative AI Revolutionizes Pharmaceutical Research: Accelerating Drug Discovery from Years to Months
Generative AI in Drug Discovery USA Overview Generative AI is profoundly transforming pharmaceutical research, primarily through de novo drug design, protein structure prediction, and biologics design. It enables the computational genera... -
Advances in 3D Bioprinting for Organoid Construction: Enhancing Physiological Relevance and Promoting Diverse Biomedical Applications
PMC (NIH) International Overview A comprehensive review article highlights recent advancements in 3D bioprinting technology for organoid construction. This technique overcomes challenges of traditional organoid culture methods by precise... -
Sanofi Unveils ‘Dual-Targeting Library 2.0’ to Accelerate Novel Bispecific Therapeutic Design
Sanofi France Overview Sanofi has announced its innovative 'Dual-Targeting Library (DTL) 2.0' approach for designing novel bispecific therapeutics. This strategy combines monospecific antibodies and nanobodies to build extensive bispecif... -
Converging 3D Bioprinting and Organoids: A Novel Approach Revolutionizing Disease Modeling and Regenerative Medicine
Oxford Academic (Regenerative Biomaterials) Global Overview The convergence of 3D bioprinting and organoid technology presents a new paradigm poised to revolutionize disease modeling, drug screening, and regenerative medicine. 3D bioprin... -
Verseon Champions Physics-Based Molecular Design to Transcend AI’s Training Data in Drug Discovery
Endpoints News USA Overview Verseon asserts that physics-based molecular design can reach chemical spaces beyond the limitations of traditional screening and generative AI training data, opening untapped drug discovery realms. Their Deep... -
Large Models Reshape Chemistry: Generative AI Drives Novel Molecular Design in Drug Discovery
Google Cloud Vertex AI Search USA Overview Generative AI is fundamentally transforming drug chemistry by creating novel molecular structures rather than merely screening existing ones. These large machine learning models learn patterns o... -
Generative AI Accelerates Drug Discovery: Reshaping Molecular Design and Translational Decision-Making
Google Cloud Vertex AI Search USA Overview Generative AI is poised to revolutionize the entire drug discovery pipeline, from initial molecular design and chemical space exploration to ADMET prediction and crucial translational decision-m...
