Century Therapeutics Seeks Director to Lead Large-Scale Cell Therapy Process Development for Clinical and Commercial Programs

JobLeads (Century Therapeutics, Inc.) USA

Overview

Century Therapeutics is recruiting a Director of Large-Scale Process Development to lead scale-up strategies for bioreactor expansion, harvesting, and fill/finish operations in their clinical and commercial cell therapy programs. This role will drive cGMP-compliant, cost-effective manufacturing, working closely with MSAT, Regulatory, and Manufacturing teams to transfer processes to production and support regulatory submissions. The position is critical for advancing their cell therapy pipeline towards commercialization.

In Depth

Background

The successful commercialization of cell therapies hinges not only on clinical efficacy but also on the ability to manufacture these complex biological products at scale, consistently, and cost-effectively under stringent cGMP guidelines. As cell therapy candidates advance through clinical development, the transition from small-scale laboratory processes to large-scale clinical and commercial manufacturing requires specialized expertise in process development and optimization. Century Therapeutics, a leader in allogeneic iPSC-derived cell therapies, is actively building out these capabilities.

Key Findings

• Century Therapeutics is actively seeking a Director, Large-Scale Cell Therapy Process Development.
• This role is responsible for leading the development and implementation of scale-up strategies for critical manufacturing steps, including:
  • Bioreactor expansion to achieve necessary cell yields.
  • Efficient harvesting methods.
  • Robust fill/finish operations for clinical and commercial cell therapy programs.
• A primary objective is to ensure that manufacturing processes are both cGMP-compliant and cost-effective.
• The Director will collaborate closely with various internal departments, including Manufacturing Science and Technology (MSAT), Regulatory Affairs, and Manufacturing, to facilitate seamless technology transfer and support regulatory filings.

Significance & Outlook

This job opening highlights the critical industry need for specialized talent in process development as cell and gene therapies mature. Scaling cell therapy manufacturing from clinical to commercial volumes is a major bottleneck and a key determinant of a therapy’s eventual accessibility and economic viability. By investing in a dedicated leadership role for large-scale process development, Century Therapeutics demonstrates its commitment to overcoming these challenges and de-risking its pipeline. The emphasis on cGMP compliance and cost-effectiveness reflects the increasing commercial pressures in the ATMP space. Successful execution in this area will not only accelerate Century Therapeutics’ own programs but also contribute to establishing best practices for the broader cell therapy manufacturing ecosystem, ultimately benefiting patient access to these life-changing treatments.

Get our weekly technology intelligence — free

Receive an infographic that lets you judge at a glance whether each field’s analysis report is worth reading.

Subscribe Free — Weekly Tech Intelligence

By subscribing, you’ll receive Troy-Technical’s weekly technology intelligence newsletter.

• Your email and selected fields are used only to deliver the newsletter.
• We never share your information with third parties.
• You can unsubscribe anytime via the link in each email.

See our Privacy Policy for details.

Agree & Continue ▶

Takes about a minute · Unsubscribe anytime