Blood-Brain Barrier– tag –
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Blood-Brain Barrier Drug Delivery Summit (B3DD) Convenes to Overcome CNS Therapeutic Hurdles
News-Medical.net USA Overview The Blood-Brain Barrier Drug Delivery Summit (B3DD) addressed critical challenges in CNS drug delivery, focusing on bypassing the brain's selective permeability. Advanced DDS research into nanoparticles, lip... -
Alcimed Analyzes Brain Drug Delivery Barriers and Breakthroughs: Receptor-Mediated Transcytosis and LIFU as Key Enablers
Alcimed France Overview Brain drug delivery is one of modern medicine's most complex challenges due to multiple physiological barriers, notably the blood-brain barrier (BBB), which severely restricts most therapeutic molecules from enter... -
Focused Ultrasound Blood-Brain Barrier Opening: Remote Metabolic Response Discovered in Primate Brain Raises Clinical Application Challenges
PubMed (National Library of Medicine) USA Overview Low-intensity focused ultrasound (LIFU) is a promising technology for blood-brain barrier (BBB) opening for drug delivery, yet a study in non-human primate models revealed unexpected rem... -
Breaking the Blood-Brain Barrier: Nanoparticles Chart New Course for Neurodegenerative Therapies
Dove Medical Press New Zealand Overview The blood-brain barrier (BBB) prevents over 98% of small-molecule drugs and nearly all biologics from entering the brain, posing a major challenge for neurological therapies. Nanoparticles (NPs) of... -
UT MD Anderson Tackles Brain Tumor Therapy by Advancing Multiple Blood-Brain Barrier Penetration Strategies
UT MD Anderson Cancer Center USA Overview Researchers at UT MD Anderson Cancer Center are aggressively pursuing multiple research strategies to overcome the blood-brain barrier (BBB), a formidable challenge in brain tumor treatment. Whil... -
LNP Innovation Revolutionizes RNA Delivery: Advancing Tissue-Specific Targeting and Immunoprofile Optimization
Inside Therapeutics USA Overview Lipid nanoparticles (LNPs) have established themselves as the most clinically validated and advanced platform for RNA drug delivery. LNPs critically protect nucleic acids from enzymatic degradation, facil... -
Oregon State University Develops Novel Sugar-Coated Nanoparticle Therapy for Glioblastoma: Boosting Mouse Survival by 50%
Oregon State University via Medical Xpress USA Overview Researchers at Oregon State University have developed a new experimental glioblastoma treatment using sugar-coated nanoparticles to deliver genetic instructions that restore a tumor... -
Denali Therapeutics Announces Breakthroughs in Blood-Brain Barrier Biologic Delivery: AVLAYAH™ Receives FDA Accelerated Approval for Hunter Syndrome
Denali Therapeutics USA Overview Denali Therapeutics CEO Dr. Ryan Watts will deliver a plenary address at AAIC 2026, highlighting the company's breakthrough advancements in delivering biologic therapies across the blood-brain barrier (BB... -
BBB-Permeable Nanoparticles: A Novel Strategy for Breakthrough Neurodegenerative Disease Therapies
DovePress - International Journal of Nanomedicine UK Overview Research published in the 'International Journal of Nanomedicine' reports that the latest design of nanoparticles effectively crossing the blood-brain barrier (BBB) has brough... -
Ractigen’s SOD1-ALS siRNA Therapy RAG-17 Shows Significant SOD1 Reduction and Favorable Safety in Phase 1, Published in Nature Medicine
BioSpace USA Overview Ractigen Therapeutics published preclinical and positive First-in-Human Phase 1 clinical data for RAG-17, an siRNA therapy for SOD1-ALS, in Nature Medicine. The trial met primary safety endpoints with no serious adv...
