Monoclonal Antibody– tag –
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Continuous Multi-Column Chromatography Integrates and Intensifies Monoclonal Antibody Downstream Processing, Boosting Efficiency and Sustainability
BioProcess International USA Overview The integration of two chromatography steps using a continuous multi-column chromatography (MCC) system is shown to dramatically improve the efficiency and sustainability of downstream processing in ... -
Dynamic Perfusion Culture Revolutionizes Monoclonal Antibody Manufacturing: Maximizing Product Quality and Yield, Driving Continuous Biomanufacturing
Bioprocess Online USA Overview While fed-batch remains standard for mAb production, dynamic perfusion culture offers compelling opportunities to boost product quality, yield, and facility utilization by optimizing cell growth and metabol... -
ENEA’s Novel Rotating Drum Bioreactor Dramatically Boosts Monoclonal Antibody Production Yields
ENEA - Agenzia nazionale (Facebook) Italy Overview Researchers at the Italian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA) have engineered an innovative rotating drum bioreactor that significan... -
Continuous Bioprocessing Delivers Significant Gains in Biopharmaceutical Manufacturing Efficiency and Cost Reduction, Driven by 500L Single-Use Perfusion Bioreactors
BioProcess International USA Overview Biopharmaceutical manufacturers are rapidly adopting continuous bioprocessing, integrating upstream cell culture and downstream operations to boost productivity, cut costs, and reduce facility footpr... -
MDPI Study Achieves mAb Yield Maximization and Cost Reduction Through Dynamic Simulation and Optimization of Fed-Batch Bioreactors
MDPI Global Overview A research paper published in MDPI demonstrates the effectiveness of dynamic simulation and optimization methods for fed-batch bioreactors in monoclonal antibody (mAb) production. Addressing the need for higher yield... -
Separation Science Reports AI-Assisted Protein A Chromatography Optimization for mAb Purification: Real-Time Predictive Control Enhances Yield and Purity
Separation Science USA Overview Separation Science reports on a breakthrough application of AI and machine learning (ML) in optimizing Protein A chromatography for monoclonal antibody (mAb) purification. AI models accurately predict dyna... -
AI and Machine Learning Revolutionize Biologics Purification: Optimizing Monoclonal Antibody Manufacturing with Predictive Resin Life and Enhanced Yields
Separation Science UK Overview Artificial intelligence (AI) and machine learning (ML) are significantly optimizing purification processes for biologics, contributing to cost reduction and yield enhancement in monoclonal antibody (mAb) ma... -
Thermo Fisher Scientific Unveils DynaXS Single-Use Bioreactor and Global Manufacturing Expansion at BIO 2026, Boosting Cell & Gene Therapy Production
Business Wire USA Overview Thermo Fisher Scientific announced significant new manufacturing capabilities and AI-enabled research advancements at BIO International 2026, aiming to strengthen the cell and gene therapy sector. Key highlight... -
Cytiva Achieves Enhanced mAb Variant Separation and Purity Using IEX and Multimodal Resins, Optimizing Elution pH with Capto SP ImpRes
Cytiva USA Overview Cytiva's latest research demonstrates a significant improvement in separating charged monoclonal antibody (mAb) variants and achieving higher purity using ion exchange (IEX) and multimodal resins. Specifically, optimi... -
Lonza Unveils Enhanced DNA-to-IND Biologics Manufacturing Offering with 6-Month Timelines, Introducing GS Ori-Go™
PharmaSource Switzerland Overview Lonza has announced an enhanced 'DNA-to-IND' offering for biologics, aiming to achieve IND-readiness for monoclonal antibody programs in as little as six months. This accelerated timeline is supported by...
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